Evaluation of the Appropriate Size of Follicles on Success Rate in Patient Undergoing Controlled Ovarian Stimulation and Intrauterine Insemination Cycles

Document Type : Original Articles


1 Department of Obstetrics and Gynecology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

2 Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

3 Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


Objectives: Intra-Uterine Insemination (IUI) is one of the methods for infertility treatments. The size of the follicles and endometrial thickness are two important factors in pregnancy rate of patients undergoing controlled ovarian stimulation and intrauterine insemination cycles (COH-IUI). The aim of this study was to investigate the success rate of IUI and follicular size and other associated factors in infertile couples. Materials & Methods: The study group was the patients who were undergoing COH-IUI. BMI of all women recorded and ovulation induction was propelled and when there was appropriate endometrial thickness and at least one dominant follicle in trans-vaginal ultrasonography. 36 hours after HCG injection, IUI was performed. Then pregnancy rate between patients who had follicle size fewer than 20 mm and higher than 20 mm was assumed. Results: 159 cases of IUI were performed and pregnancy happened in 22(14.1 %). In non-pregnant group (134 cases), 78 cases had under 20 mm follicles and 47 cases had higher than 20 mm follicles. In pregnant group (22 cases) 10 cases had fewer than 20 mm follicles and 12 cases had higher than 20 mm follicles in the time of HCG injection. Endometrial thickness was 8.01±1.42 mm in patients with follicles more than 20 mm.Conclusion: The success rate in controlled ovarian stimulation and intrauterine insemination cycles closely related to obtaining of optimal size of follicles and endometrial thickness. 


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