Journal of Advanced Medical Sciences and Applied Technologies

Journal of Advanced Medical Sciences and Applied Technologies

Does Progesterone Suppository to Luteal Phase Support Have Any Effect on Pregnancy Rates in the Intrauterine Insemination Cycles?

Document Type : Case Study

Authors
Maryam Yasaei 1
Fallah Tafti T 1
Maryam Eftekhar 2
Razieh Dehghani-Firouzabadi 1
1 Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2 Yazd Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
10.18869/nrip.jamsat.3.2.125
Abstract
Objectives: Rate of infertility in overall is around 15-10%. Intra-Uterine Insemination (IUI) is one procedure for infertility treatment. Luteal phase support defect is a main factor in fail of pregnancy. Goal of this study was to evaluate the effect of luteal phase support with progesterone suppository in patients who undergoing IUI cycles.Materials & Methods: 100 infertile couples who were undergoing IUI treatment included in this study. Ovulation induction was done for all patients. When IUI was done, patients were distributed into two groups. The study group (n=50) received progesterone suppository and control group (n=50) doesn’t received any medicine. Then biochemical pregnancy rate, clinical pregnancy rate and abortion rate compared between two study groups. Results: There were no differences in basic characteristics between two groups. Biochemical and clinical pregnancy were parallel in the study and control groups. There were no statistically significant increases in abortion rate between the study groups (P=0.49). Conclusion: Luteal phase support by progesterone suppository does not improve the pregnancy rate of stimulated IUI cycles. 
Keywords
Progesterone
Luteal phase
Infertility
Intra-Uterine Insemination
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Journal of Advanced Medical Sciences and Applied Technologies
Volume 3, Issue 2 - Serial Number 2
12
June 2017
Pages 125-129