Nano-TiCl4.SiO2 Promoted One-Pot Synthesis of Amides or Nitriles from Aldehydes

Document Type : Original Articles


Department of Chemistry, College of Science, Yazd University, Yazd,PO Box 89195-741, I. R. Iran


This research proposes an efficient and easy procedure for the preparation of amides or nitriles from aldehydes. Such materials were prepared via one-pot three component condensation reaction of various aldehydes in the presence of nano-TiCl4.SiO2 as a catalyst under thermal conditions. All reactions proceeded in high yields and in a moderately short reaction time. Meanwhile, oximes were obtained from aldehyeds in the presence of nano-TiCl4.SiO2.


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