Shiraz University of Medical SciencesJournal of Advanced Medical Sciences and Applied Technologies2423-59032220160601Snoring, a Vexing Night Symphony or Clinical Red Flag?1971994246510.18869/nrip.jamsat.2.2.197ENMohammadNamiDepartment of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences0000-0003-1410-5340Journal Article20160618Sleep disordered breathing (SDB) is widely known to negatively affect productivity due to the resultant sleepiness. Meanwhile, the significance of snoring, upper airway resistances and sleep apnea has not been well appreciated by the general public. There has not been enough understanding about this common symptom as a major cause of various cardiovascular or neurological diseases. To properly diagnose SDB, the understanding of current development in technology and devices in the field is deemed mandatory. This brief perspective paper has been an attempt to touch on the significance of snoring as a clinically noticeable symptom especially when becomes intense and persistent. The negative impact of SDB on the so-called lung-brain axis has turned to an evolving area of experimental research in the field of sleep medicine.https://jamsat.sums.ac.ir/article_42465_1dc213b41bbe0af4b13f4c02ba8deb26.pdfShiraz University of Medical SciencesJournal of Advanced Medical Sciences and Applied Technologies2423-59032220160601Evaluation of the Effects of Mentha Spicata Extract on In-Vitro Maturation of Mouse Oocytes2002034246710.18869/nrip.jamsat.2.2.200ENSanazAlaeeDepartment of Reproductive Biology, School of Advanced Medical Sciences and Technologies, SUMS, IranJournal Article20160527In traditional medicine, Mentha spicata is widely used for many diseases, especially in digestive system. It has anti-androgenic effects thus can be used by women experiencing polycystic ovary syndrome (PCOS). Also, it has shown to possess antioxidant properties. Although beneficial, studies have shown its detrimental effect on some tissues. The present study was carried out to determine the effect of Mentha spicata extract on oocyte maturation. To this aim, germinal vesicles (GV) were obtained from ovaries of 6-8 week old female C57 mice and cultured for 24 hours in maturation media containing different concentrations of Mentha spicata extract (0, 10, 20, 40 µg/ml). Another maturation medium containing dimethyl sulfoxide (DMSO) was determined as a Mentha spicata extract solvent. After 24 hours, number of degenerated, germinal vesicle (GV), metaphase I (MI) and metaphase II (MII) oocytes were determined in each group using an inverted microscope. According to our results, the percentage of degenerated oocytes was higher in experimental groups compared to the control group. This has however not been statistically significant (P=0.473). Additionally, the percentage of GV oocytes was not different in control and experimental groups (P=0.774). The percentage of MI and MII oocytes was lower in experimental as compared to control groups, however statistically insignificant (P=0.410 and 0.855, respectively). In conclusion, Mentha spicata extract has mild detrimental effects on oocyte in vitro maturation. However, with increased concentration, its detrimental effects decrease which may be due to higher level of its antioxidants contents. Therefore addition of appropriate amounts of Mentha spicata as a natural extract in maturation medium may improves oocytes’ maturation rate.https://jamsat.sums.ac.ir/article_42467_093904480ca8899136e11ee25180e5bf.pdfShiraz University of Medical SciencesJournal of Advanced Medical Sciences and Applied Technologies2423-59032220160601Investigation of the Impact of QEEG-Based Biofeedback on Attention and Behavioral Features in Young Male Adolescents with ADHD2042124246810.18869/nrip.jamsat.2.2.204ENNaderAlirezalooDepartment of Occupational Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, IranAli SHosseiniDepartment of Occupational Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, IranEbrahimPishyarehDepartment of Occupational Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, IranMasoudNosratabadiPaarand Specialized Center for Human Enhancement, Tehran, IranHojjat AllahHaghgooDepartment of Occupational Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, IranAkbarBiglarianDepartment of Biostatistics, University of Social Welfare and Rehabilitation Sciences, Tehran, IranJournal Article20160522Introduction: Attention Deficit/Hyperactivity Disorder (ADHD) is a disorder of neurobiological behavioral system. This disorder includes features such as attention deficit, impulsivity, and chronic, disproportionate-with-growth hyperactivity which reduce the child's ability to regulate, control, organize his behavior and cause attention deficit in activity of daily living (ADL). ADHD is one of the most common childhood disorders. The aim of this study was to investigate the effect of QEEG-based biofeedback on behavioral and attention factors of 7 to 14 year-old boys diagnosed with ADHD. Method: 40 boys diagnosed with ADHD were randomly assigned into the experimental and control groups. Integrated Visual and Auditory (IVA) test and Children's Behavioral Check List (CBCL) were used before the treatment and after 8 intervening weeks of treatment in both groups. Moreover, the brain mapping (QEEG) of the experimental group was used to design a treatment protocol. The experimental group received 24 sessions of neurofeedback therapy three times a week. The acquired data was analyzed using the Analysis of Covariance (ACNOVA). Results: Our findings demonstrated a significant difference in test results between the experimental and control groups upon IVA and CBCL tests following the neurofeedback intervention. Moreover, there was a significant difference between pre- and post-tests in the neurofeedback group. Interaction effect was insignificant at the time. Conclusion: Results of the present study showed that neurofeedback can bring significant improvements in attention factors especially, sustained attention and children's externalizing behaviors. As such, neurofeedback may be considered as one of the therapeutic modalities used along with core therapies and medication, though, more research is needed to compare the clinical effects of different treatment protocols with one another.https://jamsat.sums.ac.ir/article_42468_0c813f937a1caaac11adcbfc3620d284.pdfShiraz University of Medical SciencesJournal of Advanced Medical Sciences and Applied Technologies2423-59032220160601A Comparative Analysis on Quality of Life in Mothers of Autistic, Blind, and Normal-Functioning Children2132194247010.18869/nrip.jamsat.2.2.213ENBehnazKianiDepartment of Counseling, Razi University, Kermanshah, IranMohammadNamiDepartment of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences0000-0003-1410-5340Journal Article20160623Background: Quality of life largely depends on one’s perception about different aspects life. The present investigation aimed at comparing the quality of life of mothers with autistic, blind, or normal-functioning children. Materials and Methods: This cross-sectional comparative study was done in a population of 146 mothers of children who aged 6-15 years old, in Shiraz, within the period 2013-2014. Ninety six mothers had children who were either blind or autistic, while 50 had children with no disabilities. Participants were enrolled through multi-stage cluster sampling method. The Quality of Life (QoL) questionnaire-100 was employed to collect data and one-way ANOVA was used to analyze results. Results: Findings demonstrated a significant difference in QoL of mothers with autistic, blind, and normal-functioning children. Mothers with normal-functioning children had higher levels of QoL than those with blind kids. In addition, the QoL of mothers with autistic children was lower than the other two groups. Conclusion: Considering the importance of quality of life in mothers’ life and subsequent family functioning, relevant programs need to be pursued to improve conflict resolution in distressed groups. https://jamsat.sums.ac.ir/article_42470_40dba95de9df97a0406c32b4ea181d28.pdfShiraz University of Medical SciencesJournal of Advanced Medical Sciences and Applied Technologies2423-59032220160601DNA-Directed Methylation Analysis Methodology2202234246310.18869/nrip.jamsat.2.2.220ENBaharehVakiliPoonehMokarramJournal Article20160620Epigenetics alterations, especially DNA methylation, play a critical role in control of gene expressions. Abnormal patterns of methylation are observed in early-stages of many cancers. Therefore, methylation analysis is useful in primary detection of tumors. Advances knowledge about the functional role of aberrant epigenetic modifications as potential biomarkers for cancer, have attracted considerable interest to pursue such investigations. Currently, many methodologies are available to distinguish methylation patterns, however, none is considered as the ‘gold-standard’ technique. This paper is an overview on some convenient methylation analysis methods.https://jamsat.sums.ac.ir/article_42463_b221bddcdfcc5148a648c67a9a22d960.pdfShiraz University of Medical SciencesJournal of Advanced Medical Sciences and Applied Technologies2423-59032220160601An Overview on the Health Benefits and Production of Fermented Functional Foods2242334246910.18869/nrip.jamsat.2.2.224ENCatherineLiangFaculty of Science and Engineering, The University of Waikato, Hamilton, New ZealandZahraSarabadaniFaculty of Science and Engineering, The University of Waikato, Hamilton, New ZealandAydinBerenjianFaculty of Science and Engineering, The University of Waikato, Hamilton, New ZealandJournal Article20160624Functional foods have a large and growing global market and are regarded as one of the most actively researched areas of food science. The growth in popularity of functional foods is attributed to the phenomena of consumer health care, increasing health awareness and knowledge in the many benefits of functional foods. Common benefits of functional foods include reduction of disease, health maintenance and prevention of nutrition related diseases. In this review, the current state and challenges for the production of functional foods by the help of bioprocess engineering are investigated. The present review also revisits the commercial impediments to provide insight for future works.https://jamsat.sums.ac.ir/article_42469_129eb17345640e7946c97907d497c501.pdfShiraz University of Medical SciencesJournal of Advanced Medical Sciences and Applied Technologies2423-59032220160601Bilateral Subdural Hygroma in a Case with Sylvian Arachnoid Cyst2342374246410.18869/nrip.jamsat.2.2.234ENMortezaMotaghedifardGeneral physician, Trauma Research Center, Kashan University of Medical Sciences, Kashan, IR Iran.AhmadTalebianProfessor of Pediatrics Neurology, Department of Pediatrics, Kashan University of Medical Sciences, Kashan, IR Iran.EsmaeilFakharianProfessor of neurosurgery, Department of Neurosurgery, Kashan University of Medical Sciences, Kashan, IR Iran.AmirhosseinJafarianGeneral physician, Trauma Research Center, Kashan University of Medical Sciences, Kashan, IR Iran.SaeedBanaeeAssistant professor of neurosurgery, Department of Neurosurgery, Kashan University of Medical Sciences, Kashan, IR Iran.Journal Article20160415Arachnoid cysts are congenital lesions arising from the arachnoid membrane. The incidence of arachnoid cysts in the general population is around 0.1% and their most common location is the middle fossa. Arachnoid cysts usually present during the childhood and are identified incidentally. When symptomatic, the most common presentations include headache and seizure. The popular treatment for this lesion is surgery. In this case report, we describe a 12 year-old boy with a middle cranial fossa arachnoid cyst presenting with progressive headache, and bilateral subdural hygroma following a trivial head trauma.https://jamsat.sums.ac.ir/article_42464_f138b2d26e543f5f9eed30a3c192213a.pdfShiraz University of Medical SciencesJournal of Advanced Medical Sciences and Applied Technologies2423-59032220160601The Second Interdisciplinary Seminar on Brain and Cognition, Shiraz, Iran2382434246610.18869/nrip.jamsat.2.2.238ENAbolfazlAlipourStudent Research Committee, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, IranJournal Article20160615 Recent advances in brain and cognitive science studies have revolutionized concepts in neural dynamics, regulating mechanisms, coding systems and information processing networks which govern our function and behavior. Hidden aspects of neurological and psychiatric diseases are being understood and hopes for their treatment are emerging. As such, advancing neuroscience knowledge and its innovative applications should be fostered to empower both scientists and practitioners in serving the public by optimizing self-regulatory brain function. To reach the above, a key initiative has been “organizing interdisciplinary seminars on neuroscience” at SUMS. The second Interdisciplinary Seminar on Brain and Cognition (ISBC-2) was held on June 5, 2016 at SUMS. The conference, as the theme suggests, aimed to bring forward the interdisciplinary dialogue between neuroscience, cognitive and also computational approaches in study of Brain and Cognition. This paper is a brief report of the discussed topics in the four panels of ISBC-2, namely cognitive, systems, computational and clinical neuroscience. https://jamsat.sums.ac.ir/article_42466_efe5b77208f94188232bf271f096c9d5.pdf