TY - JOUR ID - 48388 TI - Association of Sleep Spindles, Sleep Apnea, and Other Polysomnography Parameters; a Single Center Preliminarily Report JO - Journal of Advanced Medical Sciences and Applied Technologies JA - JAMSAT LA - en SN - 2423-5903 AU - Gholamzadeh, Mohammad Javad AU - Fereidooni, Reza AD - Students’ Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran AD - Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran Y1 - 2021 PY - 2021 VL - 6 IS - 1 SP - 81 EP - 85 KW - Sleep Spindle KW - Obstructive Sleep Apnea KW - Polysomnography DO - 10.30476/jamsat.2021.48388 N2 - Introduction: Obstructive sleep apnea (OSA) is associated with arousals due to thecessation of breathing during sleep. On the other hand, sleep spindles, an EEG wave mainlyseen in stage 2 of non-REM sleep (N2), are responsible for many functions including themaintenance of sleep. We aimed to investigate the association between sleep spindles andOSA and compare the additional polysomnography (PSG) metrics in a group of patientswith OSA.Materials and Method: Fifty consecutive patients with moderate and severe OSA wererecruited. Association of apnea-hypopnea index (AHI) with spindles in N2 and arousalswere evaluated. Other PSG metrics were compared in the moderate versus severe group.Results: Body mass and snore indices were significantly more in the severe group (p=0.002and p<0.001, respectively). Arousals were more frequently seen in severe OSA cases(p=0.064). Sleep spindle index did not have any relationship with AHI and the numberof arousals. However, arousals were weakly correlated with AHI (Spearman’s rho= 0.293,p=0.039) and snore index (Spearman’s rho= 0.365, p=0.010).Conclusion: Severity of OSA did not show a clear correlation with spindle density in N2.Further studies with larger samples and a control group are needed to prove a relationshipbetween sleep spindles and OSA. UR - https://jamsat.sums.ac.ir/article_48388.html L1 - https://jamsat.sums.ac.ir/article_48388_d75adddf15e58b4d9fcd4643d807d1b1.pdf ER -