%0 Journal Article %T Demystifying the Biophoton-Induced Cellular Growth: A Simple Model %J Journal of Advanced Medical Sciences and Applied Technologies %I Shiraz University of Medical Sciences %Z 2423-5903 %A Alipour, Abolfazl %D 2015 %\ 12/31/2015 %V 1 %N 2 %P 112-115 %! Demystifying the Biophoton-Induced Cellular Growth: A Simple Model %K None-Chemical Distant Cellular Interactions (NCDCI) %K Biophoton %K Cryptochrome %K Cell growth %R 10.18869/nrip.jamsat.1.2.112 %X Background: None-Chemical Distant Cellular Interactions (NCDCI) are among the unexplained issues in cell biology. One example of such interactions is the biophoton-induced growth. In this process, photon emissions from one cell can induce mitosis in other cells while they are chemically separated. This effect is evident among many species. Hypothesis: It is hypothesized that some simple but universal molecular pathways, which include photoreceptor proteins, modulators of cell cycle and circadian rhythm, can explain this phenomenon. Particularly, existing experimental data has been used to support the hypothesis that exposure of cellular structures to visible light photons deactivates the cryptochrome protein and this deactivation disinhibits cell growth. This disinhibition happens through the influx of Ca2+ cations and subsequent activation of the downstream mitogenic pathways. Conclusion: While the existing lines of evidence are mixed and equivocal, current hypothesis provides a testable framework for further experimental investigation. The present model and its predictions can be used as a well-documented platform to address the mechanisms of None-Chemical Distant Cellular Interactions in biological systems. %U https://jamsat.sums.ac.ir/article_42447_af0bf2d43ef00d421825e34ee167b316.pdf